發表著作

1.          J. H. Lai, T. F. She, Y. M. Juang, Y. G. Tsay, J. J. W. Chen*, C. C. Lai*, 2012, Comparative Proteomic Profiling of Human Lung Adenocarcinoma Cells (CL 1-0) Expressing miR-372. Electrophoresis, in press. SCI (IF: 3.569)

2.          W. Y. Hsu, V. S. Wang, C. C. Lai*, F. J. Tsai*, 2012, Simultaneous Determination of Components Released from Dental Composite Resins in Human Saliva by Liquid Chromatography/Multiple-Stage Ion Trap Mass Spectrometry. Electrophoresis, in press. SCI (IF: 3.569)

3.          C. W. Liu, M. W. Chien, S. Y. Chen, C. S. Yu, M. Y. Liao*, C. C. Lai*, 2011, Quantum Dots Enhance Peptide Detection by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry. Anal. Chem., 83(17), 6593-6600. SCI (IF: 5.874)

4.          S. Y. Chen, Y. M. Juang, M. W. Chien, K. I. Li, C. S. Yu, C. C. Lai*, 2011, Magnetic Iron Oxide Nanoparticle Enrichment of Phosphopeptides on a Radiate Microstructure MALDI Chip. Analyst, 136(21), 4454-4459. SCI (IF: 3.913)

5.          W. Y. Hsu, W. D. Lin, Y. Tsai, C. T. Lin, H. C. Wang, L. B. Jeng, C. C. Lee, Y. C. Lin, C. C. Lai*, F. J. Tsai*, 2011, Analysis of Urinary Nucleosides as Potential Tumor Markers in Human Breast Cancer by High Performance Liquid Chromatography/Electrospray Ionization Tandem Mass Spectrometry. Clin Chim Acta., 412(19-20), 1861-1866. SCI (IF: 2.389)

6.          Y. M. Juang, C. J. Chen, C. C. Lai*, 2011, Conductive Carbon Tape as A Sample Platform for Microwave-Based MALDI MS Detection of Proteins and Phosphoproteins. Anal. Bioanal. Chem. 401(4), 1219-1229. SCI (IF: 3.841)

7.          C. W. Liu, C. C. Lai*, 2011, Effects of Electron-Transfer Coupled with Collision Induced Dissociation (ET/CID) on Doubly-Charged Peptides and Phosphopeptides. J. Am. Soc. Mass Spectrom., 22(1), 57-66. SCI (IF: 3.83)

8.          S. W. Li, C. C. Lai*, J. F. Ping, F. J. Tsai, L. Wan, Y. J. Lin, S. H. Kung, C. W. Lin*, 2011, Severe acute respiratory syndrome coronavirus papain-like protease suppressed alpha interferon induced responses through downregulation of extracellular signal-regulated kinase 1-mediated signalling pathways. J. Gen. Virol., 92(Pt5), 1127-1140. SCI (IF: 3.568)

9.          J. M. Hsu, C. T. Chen, C. K. Chou, H. P. Kuo, L. Y. Li, C. Y. Lin, H. J. Lee, Y. N. Wang, M. Liu, H. W. Liao, B. Shi, C. C. Lai, M. T. Bedford, C. H. Tsai, M. C. Hung*, 2011, Crosstalk between Arg 1175 methylation and Tyr 1173 phosphorylation negatively modulates EGFR-mediated ERK activation. Nat. Cell Biol. 13(2), 174-181. SCI (IF: 19.407)

10.       R. Zhao, S. C. Yeung, J. Chen, T. Iwakuma, C. H. Su, B. Chen, C. Qu, F. Zhang, Y. T. Chen, Y. L. Lin, D. F. Lee, F. Jin, R. Zhu, T. Shaikenov, D. Sarbassov, A. Sahin, H. Wang, H. Wang, C. C. Lai, F. J. Tsai, G. Lozano, M. H. Lee*. 2011, Subunit 6 of the COP9 signalosome promotes tumorigenesis in mice through stabilization of MDM2 and is upregulated in human cancers. J. Clin. Invest., 121(3), 851-65. (IF 14.152)

11.       Y. Wei, Y. H. Chen, L. Y. Li, J. Lang, S. P. Yeh, B. Shi, C. C. Yang, J. Y. Yang, C. Y. Lin, C. C. Lai, M. C. Hung*, 2011, CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymal stem cells. Nat. Cell Biol. 13(1), 87-94. SCI (IF: 19.407)

12.       L. Y. Li, H. Chen, Y. H. Hsieh, Y. N. Wang, H. J. Chu, Y. H. Chen, H. Y. Chen, P. J. Chien, H. T. Ma, H. C. Tsai, C. C. Lai, Y. P. Sher, H. C. Lien, C. H. Tsai, M. C. Hung*. 2011, Nuclear ErbB-2 Enhances Translation and Cell Growth by Activation of rRNA Gene Transcription. Cancer Res., 71(12), 4269-4279. (IF: 8.234)

13.       P. N. Chen, C. C. Lai, S. H. Chiu*, 2011, Self-sorting under solvent-free conditions: one-pot synthesis of a hetero[3]rotaxane. Org. Lett., 13(17), 4660-4663. SCI (IF: 5.25)

14.       S. Y. Hsueh, J. L. Ko, C. C. Lai, Y. H. Liu, S. M. Peng, S. H. Chiu*. 2011, A Metal-Free "Threading-Followed-by-Shrinking" Protocol for Rotaxane Synthesis. Angew. Chem. Int. Ed. Engl., 50(29), 6643-6646. SCI (IF: 12.73)

15.       B. Y. Wei, Y. M. Juang, C. C. Lai*, 2010, A Novel Approach for Quantitative Peptides Analysis by Selected Electron Transfer Reaction Monitoring. J. Chromatogr. A, 1217(44), 6927-6931. SCI (IF: 4.194)

16.       S. Y. Chen, K. I. Li, C. S. Yu, J. S. Wang, Y. C. Hu*, C. C. Lai*, 2010, A Radiate Microstructure MALDI Chip for Sample Concentration and Detection. Anal. Chem., 82(14), 5951-5957. SCI (IF: 5.874)

17.       W. Y. Hsu, W. D. Lin, W. L. Hwu, C. C. Lai*, F. J. Tsai*, 2010, Screening assay of very long chain Fatty acids in human plasma with multiwalled carbon nanotube-based surface-assisted laser desorption/ionization mass spectrometry. Anal. Chem., 82(16), 6814-6820. SCI (IF: 5.874)

18.       Y. M. Juang, C. Y. Lee, W. Y. Hsu, C. T. Lin, C. C. Lai*, F. J. Tsai*, 2010, Proteomic analysis of chondrocytes exposed to pressure. Biomed Chromatogr, 24(12), 1273-1282. SCI (IF: 1.545)

19.       P. C. Chang#, J. N. Sudhakar#, C. C. Lai (Co-first author)#, H. C. Chen*, 2010, Differential phosphorylation of the docking protein Gab1 by c-Src and the hepatocyte growth factor receptor regulates different aspects of cell functions. Oncogene, 29(5), 698-710. SCI (IF: 7.414)

20.       S. Y. Hsueh, C. T. Kuo, T. W. Lu, C. C. Lai, Y. H. Liu, H. F. Hsu, S. M. Peng, C. H. Chen, S. H. Chiu*, 2010, Acid/base- and anion-controllable organogels formed from a urea-based molecular switch. Angew. Chem. Int. Ed. Engl., 49(48), 9170-9173. SCI (IF: 12.73)

21.       L. Huo, Y. N. Wang, W. Xia, S. C. Hsu, C. C. Lai, L. Y. Li, W. C. Chang, Y. Wang, M. C. Hsu, Y. L. Yu, T. H. Huang, Q Ding, C. H. Chen, C. H. Tsai, M. C. Hung*, 2010, RNA helicase A is a DNA-binding partner for EGFR-mediated transcriptional activation in the nucleus. Proc Natl Acad Sci U S A., 107(37), 16125-16130. SCI (IF: 9.771)

22.       T. C. Yang, C. C. Lai, S. L. Shiu, P. H. Chuang, B. C. Tzou, Y. Y. Lin, F. J. Tsai, C. W. Lin, 2010, Japanese encephalitis virus down-regulates thioredoxin and induces ROS-mediated ASK1-ERK/p38 MAPK activation in human promonocyte cells. Microbes. Infect., 12(8-9), 643-651. (IF: 2.726)

23.       S. Y. Hsueh, C. C. Lai, S. H. Chiu*, 2010, Squaraine-Based [2]Rotaxanes that Function as Visibly Active Molecular Switches. Chemistry : a European Journal., 16(10), 2997-3000. SCI (IF: 5.476)

24.       W. Y. Hsu, T. L. Chen, W. D. Lin, F. J. Tsai, Y. Tsai, C. T. Lin, W. Y. Lo, L. B. Jeng*, C. C. Lai*, 2009, Analysis of urinary nucleosides as potential tumor markers in human colorectal cancer by high performance liquid chromatography/electrospray ionization tandem mass spectrometry. Clin Chim Acta., 402(1-2), 31-37. SCI (IF: 2.389)

25.       D. F. Lee, H. P. Kuo, M. Liu, C. K. Chou, W. Xia, Y. Du, J. Shen, C. T. Chen, L. Huo, M. C. Hsu, C. W. Li, Q. Ding, T. L. Liao, C. C. Lai, A. C. Lin, Y. H. Chang, S. F. Tsai, L. Y. Li, M. C. Hung*, 2009, KEAP1 E3 ligase-mediated downregulation of NF-kappaB signaling by targeting IKKbeta. Mol Cell, 36(1), 131-140. SCI  (IF: 14.194)

26.       C. C. Chen, Y. C. Cho, C. C. Lai, W. H. Hsu*, 2009, Purification and characterization of a new Rhizopuspepsin from Rhizopus oryzae NBRC 4749. J. Agric. Food Chem., 57(15), 6742-6747. SCI (IF: 2.816)

27.       M. J. Li, C. C. Lai, Y. H. Liu, S. M. Peng, S. H. Chiu*, 2009, Two guest complexation modes in a cyclotriveratrylene-based molecular container. Chem Commun (Camb)., 39, 5814-5816. SCI (IF: 5.787)

28.       T. C. Lin, C. C. Lai, S. H. Chiu*, 2009, A guanidinium ion-based anion- and solvent polarity-controllable molecular switch. Org. Lett., 11(3), 613-616. SCI (IF: 5.25)

29.       P. T. Chiang, N. C. Chen, C. C. Lai*, S. H. Chiu*, 2008, Direct observation of mixed-valence and radical cation dimer States of tetrathiafulvalene in solution at room temperature: association and dissociation of molecular clip dimers under oxidative control. Chemistry : a European Journal., 14(21), 6546-6552 SCI (IF: 5.476)

30.       J. L. Su, P. S. Chen, M. H. Chien, P. B. Chen, Y. H. Chen, C. C. Lai, M. C. Hung, M. L. Kuo, 2008, Further evidence for expression and function of the VEGF-C/VEGFR-3 axis in cancer cells. Cancer Cell, 13(6), 557-560. SCI (IF: 26.925)

31.       C. C. Hsu, N. C. Chen, C. C. Lai, Y. H. Liu, S. M. Peng, S. H. Chiu*, 2008, Solvent-free synthesis of the smallest rotaxane prepared to date. Angew. Chem. Int. Ed. Engl., 47(39), 7475-7478. SCI (IF: 12.73)

32.       S. Y. Hsueh, K. W. Cheng, C. C. Lai, S. H. Chiu*, 2008, Efficient solvent-free syntheses of [2]- and [4]rotaxanes, Angew. Chem. Int. Ed. Engl., 47(23), 4436-4439. SCI (IF: 12.73)

33.       W. C. Chen, C. C. Lai, Y. H. Tsai, W. Y. Lin, F. J. Tsai, 2008, Mass spectroscopic characteristics of low molecular weight proteins extracted from calcium oxalate stones: preliminary study. J. Clin. Lab Anal. 22, 77-85. SCI. (IF: 1.031)

34.       N. C. Chen, C. C. Lai, Y. H. Liu, S. M. Peng, S. H. Chiu, 2008, Parking and Restarting a Molecular Shuttle In Situ. Chemistry : a European Journal., 14(9), 2904-2908. SCI (IF: 5.476)

35.       J. Y. Yang, C. S. Zong, W. Xia, H. Yamaguchi, Q. Ding, X. Xie, J. Y. Lang, C. C. Lai, C. J. Chang, W. C. Huang, H. Huang, H. P. Kuo, D. F. Lee, L. Y. Li, H. C. Lien, X. Cheng, K. J. Chang, C. D. Hsiao, F. J. Tsai, C. H. Tsai, A. A. Sahin, W. J. Muller, G. B. Mills, D. Yu, G. N. Hortobagyi, M. C. Hung, 2008, ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation. Nat. Cell Biol., 10, 138-148. SCI (IF: 19.407)

36.       Q. Ding, L. Huo, J. Y. Yang, W. Xia, Y. Wei, Y. Liao, C. J. Chang, Y. Yang, C. C. Lai, D. F. Lee, C. J. Yen, Y. J. Chen, J. M. Hsu, H. P. Kuo, C. Y. Lin, F. J. Tsai, L. Y. Li, C. H. Tsai, M. C. Hung*, 2008, Down-regulation of myeloid cell leukemia-1 through inhibiting Erk/Pin 1 pathway by sorafenib facilitates chemosensitization in breast cancer. Cancer Res., 68(15), 6109-6117. (IF: 8.234)

37.       W. Y. Hsu, W. Y. Lo, C. C. Lai*, F. J. Tsai*, C. H. Tsai, Y. Tsai, W. D. Lin and M. C. Chao, 2007, Rapid Screening Assay of Trimethylaminuria with Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry in Urine. Rapid Commu. Mass Spectrom., 21, 1915-1919. SCI (IF: 2.846)

38.       W. Y. Lo, M. H. Tsai, Y. Tsai, C. H. Hua, F. J. Tsai, S. Y. Huang, C. H. Tsai, C. C. Lai*, 2007, Identification of Over-expressed Proteins in Oral Squamous Cell Carcinoma (OSCC) patients by Clinical Proteomic Analysis. Clin Chim Acta., 376, 101-107. SCI (IF: 2.389)

39.       C. C. Lai, M. J. Jou, S. Y. Huang, S. W. Li, L. Wan, F. J. Tsai, C. W. Lin, 2007, Proteomic Analysis of Up-regulated Proteins in Human Promonocyte Cells Expressing SARS Coronavirus 3C-Like Protease. Proteomics, 7, 1446-1460. SCI (IF: 5.074)

40.       W. Y. Lo, C. C. Lai (Co-first author), C. H. Hua, M. H. Tsai, S. Y. Huang, C. H. Tsai, F. J. Tsai, 2007, S100A8 is identified as a biomarker of HPV18 infected oral squamous cell carcinomas by suppression subtraction hybridization, clinical proteomics analysis and immunohistochemistry staining. J. Proteome. Res. 6, 2143-2151. (IF: 5.46)

41.       許维儀、賴建成*、蔡輔仁、林瑋德, 2007, 質譜術於臨床代謝體學之應用. Chemistry (The Chinese Chemical Society, Taipei), 65, 169-185.

42.       D. F. Lee, H. P. Kuo, C. T. Chen, J. M. Hsu, H. L. Sun, C. K. Chou, Y. Wei, L. Y. Li, B. Ping, W. C. Huang, X. He, J.Y. Hung, C. C. Lai, Q. Ding, J. L. Su, J. Y. Yang, A. A. Sahin, G. N. Hortobagyi, F. J. Tsai, C. H. Tsai, and M. C. Hung, 2007, Suppression of TSC1 by IKKb confers tumor angiogenesis through the mTOR pathway. Cell, 130, 440-455. SCI (IF: 32.406)

43.       Y. L. Huang, W. C. Hung, C. C. Lai, Y. H. Liu, S. M. Peng, S. H. Chiu*, 2007, Using Acetate Anions To Induce Translational Isomerization in a Neutral Urea-Based Molecular Switch. Angew. Chem. Int. Ed. Engl., 46, 6629-6633. SCI (IF: 12.73)

44.       S. Y. Hsueh, C. C. Lai,, Y. H. Liu, S. M. Peng, S. H. Chiu, 2007, Highly Selective Na(+)-Templated Formation of [2]Pseudorotaxanes Exhibiting Significant Optical Outputs. Angew. Chem. Int. Ed. Engl. 46, 2013-2017. SCI (IF: 12.73)

45.       C. W. Chiu, C. C. Lai,, S. H. Chiu, 2007, Threading-Followed-by-Swelling: A New Protocol for Rotaxane Synthesis. J. Am. Chem. Soc. 129, 3500-3501. SCI (IF: 9.023) (Highlighted in Science Magazine (Editors Choice): Science, 2007, 315, 1639)

46.       C. F. Lin, C. C. Lai, Y. H. Liu, S. M. Peng, S. H. Chiu, 2007, Use of Anions to Allow Translational Isomerism of a [2]Rotaxane. Chemistry : a European Journal., 13, 4350-4355. SCI (IF: 5.476)

47.       H. J. Lin, C. C. Lai,, P. D. Chao Lee, S. S. Fan, Y. Tsai, S. Y. Huang, L. Wan, F. J. Tsai, 2007, Aloe-emodin metabolites protected N-methyl-d-aspartate-treated retinal ganglion cells by cu-zn superoxide dismutase. J. Ocul. Pharmacol. Ther. 23, 152-171. SCI (IF: 1.609)

48.       S. Y. Hsueh, C. C. Lai, Y. H. Liu, Y. Wang, S. M. Peng, S. H. Chiu, 2007, Protecting a squaraine near-IR dye through its incorporation in a slippage-derived [2]rotaxane. Org. Lett., 9, 4523-4526. SCI (IF: 5.25)

49.       W. D. Lin, C. H. Wang, C. C. Lee, C. C. Lai,, Y. Tsai, F. J. Tsai, 2007, Genetic mutation profile of isovaleric acidemia patients in Taiwan. Molecular Genetics and Metabolism, 90, 134-139. SCI (IF: 3.539)

50.       C. F. Lin, Y. H. Liu, C. C. Lai, S. M. Peng, S. H. Chiu, 2006*, Precise Facial Control in Threading Guests into a Molecular Cage and the Formation of a Turtlelike Supramolecular Complex. Angew. Chem. Int. Ed. Engl. 45, 3176-3181. (IF: 12.73)

51.       K. W. Cheng, C. C. Lai,, P. T. Chiang, S. H. Chiu, 2006, Reading the operation of an acid/base-controllable molecular switch by naked eye. Chem Commun (Camb)., 27, 2854-2856. SCI (IF: 5.787)

52.       C. W. Lin, F. J. Tsai, L. Wan, C. C. Lai,, K. H. Lin, T. H. Hsieh, S. Y. Shiu, J. Y. Li, 2005, Binding interaction of SARS coronavirus 3CL(pro) protease with vacuolar-H(+) ATPase G1 subunit, FEBS Lett., 579, 6089-6094. SCI. (IF: 3.601)

53.       C. W. Lin, F. J. Tsai, C. H. Tsai, C. C. Lai,, L. Wan, T. Y. Ho, C. C. Hsieh, P. D. Lee Chao, 2005, Anti-SARS coronavirus 3C-like protease effects of Isatis indigotica root and plant-derived phenolic compounds, Antiviral Res, 68, 36-42. (IF: 4.439)

54.       Q. Q. Ding, W. Xia, J. C. Liu, J. Y. Yang, D. F. Lee, J. Xia, G. Bartholomeu, Y. Li, Y. Pan, Z. Li, R. C. Bargou, J. Qin, C. C. Lai,, F. J. Tsai, C. H. Tsai, M. C. Hung. 2005, Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin. Mol Cell, 19, 159-170. SCI  (IF: 14.194)

55.       F. C. Hsu, T. J. Ho, C. C. Lai,, C. F. Lin, H. P. Chen, 2005, Cloning, sequencing, expression, and single-step purification of the adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase (CobU) from Salmonella typhimurium ATCC 19585. Protein Expression and Purification. 42, 178-181. SCI (IF: 1.644)

56.       W. D. Lin, C. H. Wang, C. C. Lai,, C. C. Lee, F. J. Tsai, 2004, Genetic and biochemical study in a patient with glutaric academia type I. J. Formos. Med. Assoc. 103, 549-554. (IF: 1.125)

57.       賴建成*、蔡輔仁,質譜術於臨床醫學上之應用,科儀新知,2003.25(1)18 ~ 32

58.       C. C. Lai,, C. H. Tsai, F. J. Tsai, J. Y. Wu, W. D. Lin and C. C. Lee, 2002, Rapid screening assay of congenital adrenal hyperplasia by measuirng 17 a-hydroxyprogesterone with high performance liquid chromatography/ electrospray ionization tandem mass spectro-metry from dried blood spots. J. Clin. Lab Anal.  16, 20-25. SCI. (IF: 1.031)

59.       C. C. Lai,, C. H. Tsai, F. J. Tsai, C. C. Lee and W. D. Lin, 2002, Monitoring of congenital adrenal hyperplasia by microbore HPLC-electrospray ionization tandem mass spectrometry of dried blood spots, Clin. Chem. 48. 354-356. SCI (IF: 6.886)

60.       C. C. Lai,, G. R. Her, 2002, Analysis of N-glycosylation of Phospholipase A2 from Venom of Individual Bees by Microbore High-Performance Liquid Chromatography-Electrospray Mass Spectrometry Using an Ion Trap Mass Spectrometer. J. Chromatogr B. 766, 243-250. SCI (IF: 2.971)

61.       W. D. Lin, J. Y. Wu, C. C. Lai,, F. J. Tsai, C. H. Tsai, S. P. Lin, D. M. Niu, 2001, A Pilot Study of Neonatal Screening by Electrospray Ionization Tandem Mass Spectrometry in Taiwan, Acta Paediatr. Taiwan. 42, 224-259. (J=1)

62.       C. C. Lai,, C. H. Tsai, F. J. Tsai, C. C. Lee and W. D. Lin, 2001, Rapid monitoring assay of congenital adrenal hyperplasia with microbore high-performance liquid chromatography/electrospray ionization tandem mass spectrometry from dried blood spots, Rapid Commu. Mass Spectrom. 15, 2145-2151. SCI (IF: 2.846)

63.       C. C. Lai,, G. R. Her, 2000, September, Analysis of Glycoforms of Phospholipase A2 from Honeybee Venom by Capillary Electrophoresis/Electrospray Mass Spectrometry, Rapid Commu. Mass Spectrom. 14, 2012-2018. SCI (IF: 2.846)

64.       C. C. Lai,, P. L. Tsai, C. Yu and G. R. Her, 2000, January, Analysis of a Commercial Preparation of Erythromycin Estolates by Mass Spectrometry/Mass Spectrometry and High Performance Liquid Chromatography/Electrospray Ionization-Mass Spectrometry/Mass Spectrometry Using an Ion Trap Mass Spectrometer, Rapid Commu. Mass Spectrom. 14, 468-475. SCI, (IF: 2.846)

65.       C. C. Lai, and G. R. Her, 1998, January, The Research of Thermal Desorption-Gas Chromatography in Industrial Toxic Materials--Dichloroethane, Trichloroethylene, Methyl Isobutyl Ketone and Ethylacetate. 勞委會委託計畫IOSH86-A305, 1-52.

66.       D. D. Ju, C. C. Lai, and G. R. Her, 1997, April, Analysis of gangliosides by capillary zone electrophoresis and capillary zone electrophoresis-electrospray mass spectrometry, J. Chromatogr. A. 779, 195-203. SCI, (IF: 4.194)